UI Hospitals and Clinics

Peptic Ulcers

A peptic ulcer is a sore in the lining of the stomach, duodenum, or esophagus that is most often caused by either the germ Helicobacter pylori (H. pylori) or the use of nonsteroidal anti-inflammatory drugs (NSAIDs), such as aspirin and ibuprofen.

Symptoms of peptic ulcers include pain that:

  • starts between meals or during the night.
  • briefly stops if you eat or take antacids.
  • lasts for minutes to hours.
  • comes and goes for several days or weeks.

Other symptoms may include:

  • Weight loss
  • Poor appetite
  • Bloating
  • Burping
  • Vomiting
  • Feeling sick to your stomach

If the cause of your ulcer is the H.pylori germ, your treatment may include antibiotics. If your ulcer is caused by NSAIDS, you and your physician will decide on a treatment plan.

Care Team