Urology Clinical Research

Urology Volunteer Research Registry

Learn about or register for participation in future Department of Urology clinical research.

Adults with Pelvic Pain

Men and women age 18 and older with pelvic pain or discomfort associated with frequent urination or urgency to urinate, as well as adult men and women with pelvic pain from interstitial cystitis or chronic prostatitis (chronic inflammation around the prostate) are invited to participate in a University of Iowa research study on the conditions.

The study aims to help reveal what causes the conditions with the goal of improving diagnosis and treatment. However, the study itself does not include treatment.

Both interstitial cystitis and chronic prostatitis can cause pain or discomfort in the pelvis or lower abdomen and the need to urinate more often than normal.

The study involves three visits to UI Hospitals and Clinics over one year. Each visit will last three to four hours. The visits include blood, urine and DNA tests, a physical exam, and, for women, a pelvic exam. Participants also will take a pain test.

In addition, participants will answer health questions online every few weeks. These questionnaires each take an average of 15 minutes.

Women who are pregnant are not eligible to participate in the study.

The study tests are provided at no cost. Compensation is available. The study is funded by the National Institutes of Health.

For more information, contact Mary Eno, study coordinator, at 866-309-0834 or mary-eno@uiowa.edu.

Adults with Chronic Fatigue, Fibromyalgia or Irritable Bowel

Men and women age 18 and older with chronic fatigue syndrome, fibromyalgia or irritable bowel problems who do not have pelvic pain are invited to participate in a University of Iowa research study.

Information about people with these chronic conditions will be compared to information about people with other conditions that cause pelvic pain and the need to urinate more often than normal. The study does not involve any treatment.

The study aims to help reveal what causes certain painful urinary conditions, with the goal of improving diagnosis and treatment.

For the participants with chronic fatigue syndrome, fibromyalgia or irritable bowel problems, the study involves one three-hour visit to UI Hospitals and Clinics. The visit includes blood, urine and DNA tests, a physical exam, and, for women, a pelvic exam. Participants also will take a pain test and answer questionnaires.

Women who are pregnant are not eligible to participate in the study.

The study tests are provided at no cost. Compensation is available. The study is funded by the National Institutes of Health.

For more information, contact Mary Eno, study coordinator, at 866-309-0834 or mary-eno@uiowa.edu.

Phase II Study of Adenovirus/PSA Vaccine in Men with Recurrent or Hormone Refractory Prostate Cancer

The University of Iowa Department of Urology and the Holden Clinical Cancer Center are conducting a clinical research study of a gene therapy vaccine for recurrent prostate cancer.

We are seeking patients with recurrence of prostate cancer after surgery, radiation therapy, or hormonal treatment.

All prostate cancer patients who are interested in this study will be carefully screened for participation. Not all patients will qualify for this study.

Those selected to participate will receive three vaccinations (shots) 30 days apart, and will be watched closely for development of immune response to the vaccine and changes in their prostate cancer.

To learn more about enrolling in this clinical research study, please contact Pamela Zehr, Clinical Research Coordinator, at 319-353-8914, or pamela-zehr@uiowa.edu.