The goal of the Imaging Program is to foster interdisciplinary research that integrates modern medical imaging techniques into basic, translational, and clinical cancer research studies. The methodologies will include computed tomography (CT), magnetic resonance imaging (MRI), ultrasound, positron emission tomography (PET), gamma scintigraphy, optical imaging, and autoradiography. Metabolic imaging extends the capability of imaging well beyond anatomy. It includes imaging blood flow, vascular permeability, metabolic rates (glucose, oxygen, DNA synthesis, protein synthesis, membrane synthesis), receptor distribution and density (estrogen, testosterone, somatostatin), apoptosis, angiogenesis, cell trafficking, and reporter gene activation. Members of the imaging program are working in all these areas. The importance of having an Imaging Program is that it brings these investigators together to collaborate, and share ideas, imaging strategies, and data analysis methods.
The Imaging Program has the following specific areas of focus:
- Metabolic assessment of response to therapy
- Iodine symporter as a reporter gene and as a novel therapy
- Cell trafficking
- Development of new radiopharmaceuticals
- Development of novel analysis methodologies