Large Scale Digital Cell Analysis System

Director: Fiorenza Ianzini, PhD, Assistant Professor
Office Phone: 319-335-6637
Lab: 319-335-6544 or 319-335-6542
LSDCAS: 319-335-7974
Office: 145B MRC
fiorenza-Ianzini@uiowa.edu
Technical Director: Michael A. Mackey, PhD, Associate Professor
Phone: 319-335-6058
Office: Biomedical Engineering 5013 Seamans Center
michael-mackey@uiowa.edu

Purpose

The Large Scale Digital Cell Analysis System Core provides for the development of new data analysis/visualization tools for use in biomedical research. The Core can make phase-contrast or fluorescent cell digital movies from thousands of microscope fields acquired for up to one month. With further development it is expected that the Large Scale Digital Cell Analysis System (LSDCAS) will become an important tool for molecular imaging of living cells. LSDCAS is unique; no instrument with its capabilities is available anywhere else.

Services Provided

  • LSDCAS is an automated cell analysis system capable of analyzing thousands of live cells in a single experiment. The overall philosophy underlying the LSDCAS project is to apply engineering principles towards problems of general biological interest.
  • Can make phase-contrast or fluorescent cell digital movies from thousands of microscope fields acquired for up to one month
  • Cells are kept under controlled laboratory conditions
  • LSDCAS does not perturb living cell cultures
  • With further development it is expected that LSDCAS will become an important tool for molecular imaging of living cells
  • LSDCAS is unique; no instrument with its capabilities is available anywhere else