UI Hospitals and Clinics

Clinical Trial Details

Short Title
Central Sensitization and Individual Differences
Official Title

Central vs Peripheral Sensitization and the Role of Individual Difference in Acute Myalgia


Healthy volunteers ages 18 to 55, with no serious medical conditions or current pain, are invited to participate in a study involving temporary muscle soreness from an infusion of a slightly acidic or normal saline solution. Visits also include questionnaires, collecting a saliva sample, and sensations of pressure, heat or cold water on the arm. There will be three visits: approximately 1.5 hours/visit.

Compensation available. 

Start Date
April 2, 2014
End Date
January 23, 2015
Gender Preference
Age Group
18 - 55 years
Principal Investigator
Laura Frey Law
Contact Info

Contact Jackie Loesche at 319-335-9795 or email jacquelyn-loesche@uiowa.edu

Physical Therapy & Rehabilitation Science
central sensitization ; Enter keyword ; experimental muscle soreness ; pain perception ; personality traits ;

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