UI Hospitals and Clinics

Clinical Trial Details

Short Title
Official Title

A Study Evaluating Limited Target Volume Boost Irradiation and Reduced Dose Craniospinal Radiotherapy and Chemotherapy in Children with Newly Diagnosed Standard Risk Medulloblastoma - A Phase III, Double Randomized Trial (ACNS0331)


The main purpose of this study is to find out if reducing the overall dose of radiation to the brain and spine will reduce rates of survival in children with medulloblastoma.  The study will also look at whether reducing the volume of radiation given during the boost will reduce survival rates in children with medulloblastoma.

Start Date
January 18, 2005
End Date
January 18, 2015
Gender Preference
Age Group
3 - 22 years
Principal Investigator
Ayman El-Sheikh, MD
Contact Info

Victoria Scaccia, 319-356-7875

Department or Field of Study
200410785 ; cancer ; El-Sheikh ; medulloblastoma ; pediatric ; phase three ;

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