Participants in this research study have been diagnosed with multiple myeloma. Multiple myeloma is a cancer of the plasma cells, found in bone marrow, the blood-producing tissue that fills in spaces within bone. This study is being done to see if the investigational drug (tabalumab) is safe and how well it work to help people with this particular cancer. Researchers also want to investigate how much tabalumab should be given. Does tabalumab with bortezomib and dexamethasone help people with myeloma. Also, to see if the combination of drugs is safe and what side effects are associated with them.