UI Hospitals and Clinics

Clinical Trial Details

Short Title
Official Title
High Dose Granulocyte Transfusions for the Treatment of Infection in Neutropenia (The RING Study: Resolving Infection in Neutropenia with Granulocytes) (25)

Individuals often develop serious infections when their granulocyte counts are very low. The purpose of this research study is to determine the effects of granulocyte transfusion therapy (both helpful and harmful) in the treatment of individuals who have serious infections and low granulocyte (infection fighting cells) counts as a result of chemotherapy or stem cell transplantation.

Two treatment groups will be used in this study. The first group will receive standard antibiotic therapy (medications that are used to fight infections). The second group will receive standard antibiotic therapy plus granulocyte transfusions (white blood cells or infection fighting cells).

Start Date
June 6, 2008
End Date
June 6, 2018
Gender Preference
Age Group
0 - 99 years
Principal Investigator
Ronald G. Strauss, MD
Contact Info

Ronald Strauss, 319-384-4551

antibiotic therapy ; cancer ; chemotherapy ; granulocyte counts ; granulocyte transfusion therapy ; IRB#200804727 ; pediatric ; phase 3 ; phase III ; stem cell transplantation ; strauss ;

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