University of Iowa Hospitals and Clinics

Clinical Trial Details

Short Title
Lenalidomide/dexamethasone With or Without Elotuzumab Previously Untreated Multiple Myeloma
Official Title

A Phase 3, Randomized, Open Label Trial of Lenalidomide/dexamethasone With or Without Elotuzumab in Subjects with Previously Untreated Multiple Myeloma

Description

Participants in this study have been diagnosed with multiple myeloma and have not yet been treated. Multiple myeloma is a cancer of the plasma cell, which is an important part of the immune system. The purpose of this study is to determine if elotuzumab given with lenalidomide and dexamethasone is more effective in the initial treatment of multiple myeloma compared with a standard treatment of lenalidomide and dexamethasone alone. This study will also assess the safety of the combination of drugs along with how well the participant's body will process elotuzumab. Treatment will continue until the disease gets worse, or there are unacceptable side effect, or participant or their doctor decides it is not in their best interest to participate any longer.

Start Date
November 1, 2011
End Date
May 16, 2014
Gender Preference
None
Age Group
18 - 99 years
Principal Investigator
Donald MacFarlane, MD, PhD
Contact Info

Karen Parrott, 319-353-6347

Department
Hematology/Oncology
Keywords
cancer ; hohl ; IRB#201106885 ; phase 3 ; phase III ;

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