AAML08B1 - Biology Study of Transient Myeloproliferative Disorder (TMD) in Children with Down Syndrome (DS)
This study is organized by Children's Oncology Group (COG). COG is an international research group that conducts clinical trials for children with cancer. Participants in this study are children who have been diagnosed with a condition called Transient Myeloproliferative Disorder (TMD).
TMD is found in young babies (less than 3 months old) with Down syndrome and is caused by abnormal blood cells that travel throughout the body. TMD can be life threatening if a subject develops any of the following symptoms: swelling of the organs, enlarged liver, and/or heart and lung problems. The condition of TMD in children with Down syndrome is not well understood. More information about TMD would help doctors to determine the best study treatment for TMD in the future. The purpose of this study is to collect blood samples from TMD subjects for medical research.