University of Iowa Hospitals and Clinics
Randomized Trial for Newly Diagnosed High Risk B-Precursor Acute Lymphoblastic Leukemia
AALL1131: A Phase III Randomized Trial for newly diagnosed high risk B-precursor acute lymphoblastic leukemia (ALL) testing clofarabine (IND 73789) in the very high risk stratum
Leukemia is cancer of blood cells. It develops in the bone marrow, which is the soft, spongy center of the bones that produces the three major blood cells: white blood cells to fight infection; red blood cells that carry oxygen; and platelets that help blood clot and stop bleeding. The term ‘risk’ refers to the chance of the cancer coming back after treatment
Your ALL may be classified as “High Risk” for several reasons:
This study is organized by Children's Oncology Group (COG). The purpose of the study is to closely monitor patients, with the aim of reducing the number of unintended and unwanted results of treatment (serious side effects) and deaths among children and adolescents with DS HR-ALL.
Approximately 4 people will take part in this study conducted by investigators at the University of Iowa. The total number of people enrolled nationally on this study is expected to be 4450.
Victoria Scaccia, (319) 356-7875
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