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Showing 31 - 35 of 41 results
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Effects of Isoprenoid Biosynthesis Inhibition on Primary Leukemia and Myeloma Cells

Principal Investigator: Raymond Hohl, MD

The purpose of this research study is to study how the cancer cells respond to different drugs. This study does involve any treatment and we will use blood and/or bone marrow collected from subjects for tests in our laboratory.

age group:0 to 99 years trial start date:January 5, 2007
Gender Preference:none Trial End Date: January 5, 2017
Contact Info:

Mary Schall, 319-356-3516

Keywords: blood ; bone marrow ; cancer ; hohl ; IRB#200610770 ; pediatric ; pilot

Renal Tumors Classification, Biology and Banking Study (AREN03B2); 0/30

Principal Investigator:Ayman El-Sheikh, MD

The purpose of this research study is: 1) To find out information about the patient's tumor to help their study doctors know which is the best study treatment with the least side effects; 2) To study kidney tumors so that investigators may learn more about them and find out more about how to treat patients who have these tumors; and 3) To store tumor tissue, samples of blood and urine from patients with kidney tumors so that researchers can do more studies in the future.

age group:0 to 99 years trial start date:September 21, 2006
Gender Preference:none Trial End Date: September 21, 2016
Contact Info:

Julie de la Garza, 319-356-3749

Keywords: cancer ; el-sheikh ; IRB#200605769 ; kidney ; pediatric ; phase 1 ; phase one

Genetic Epidemiology of B-cell Lymphoproliferative Disorders; SPORE

Principal Investigator: Brian Link, MD

Participants in this research study are either (1) patients at the University of Iowa Hospitals & Clinics (UIHC) who have blood or lymph node cancer; or (2) have at least two family members who are known or thought to have blood or lymph node cancer. This research involves family members because investigators want to learn whether family history or environmental exposures may increase an individual's chance of developing a blood or lymph node cancer.

age group:0 to 99 years trial start date:June 29, 2005
Gender Preference:none Trial End Date: June 29, 2015
Contact Info:

Laura Jacobus, 319-353-6125

Keywords: blood ; cancer ; IRB#200503715 ; link ; lymph node ; pediatric

Key Adverse Events After Childhood Cancer

Principal Investigator:Ayman El-Sheikh, MD

The goals of this study are 1) to look at how late-occurring complications develop among individuals going through treatment for childhood cancer, 2) to see how late-occurring complications relate to the type of cancer, stage of cancer and treatment; and 3) to compare those who have had cancer and who have a late-occurring complication to those who have had cancer and who do not have a late-occurring complication (but have the same diagnosis) in order to see if certain individuals, cancer treatment(s), or genes (the part of the cell that carries characteristics from parent to child) are related to an increased risk of getting a late-occurring complication.

age group:0 to 18 years trial start date:June 29, 2004
Gender Preference:none Trial End Date: June 29, 2014
Contact Info:

Julie de la Garza, 319-356-3749

Keywords: adverse events ; ALTE03N1 ; cancer ; complications ; el-sheikh ; IRB#200405085 ; pediatric

A Phase III Randomized Study of Chimeric Antibody 14.18 in High Risk Neuroblastoma Following Myeloablative Therapy and Autologous Stem Cell Rescue

Principal Investigator: Ayman El-Sheikh, MD

The standard treatment for neuroblastoma consists of chemotherapy, surgery, and radiation therapy. Children with high-risk neuroblastoma often respond to standard treatment at first, but there is a high risk that the cancer will come back. This study is being done to try to increase the number of children with high-risk neuroblastoma who can be cured.

age group:0 to 18 years trial start date:March 25, 2004
Gender Preference:none Trial End Date: March 25, 2014
Contact Info:

Julie de la Garza, 319-356-3749

Keywords: ANBL0032 ; cancer ; el-sheikh ; IRB#200401120 ; neuroblastoma ; pediatric ; phase 3 ; phase III
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