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Inhaled Nitric Oxide/INOpulse DS for Pulmonary Arterial Hypertension (PAH)

Principal Investigator: Sif Hansdottir, MD

This is a Phase 2, Placebo Controlled, Double-Blind, Randomized, Clinical Study to Determine Safety, Tolerability and Efficacy of Pulsed, Inhaled Nitric Oxide (iNO) Versus Placebo as Add-on Therapy in Symptomatic Subjects with Pulmonary Arterial Hypertension (PAH).

 

Please refer to www.clinicaltrials.gov identifier NCT01457781 for further information. 

age group:18 to 80 years trial start date:April 20, 2012
Gender Preference:none Trial End Date: June 14, 2013
Contact Info:

Pulmonary Hypertension Program

Page Scovel, RN

phone:  319-356-1028

fax:  319-356-7087

email:  page-scovel@uiowa.edu

Keywords: Heart ; High blood pressure in lungs ; PAH ; PH ; Pulmonary arterial hypertension ; Pulmonary diseases ; Pulmonary hypertension

Comparing Medications in Patients with with moderate Chronic Obstructive Pulmonary Disease

Principal Investigator:Alejandro Comellas MD

A Clinical Outcomes Study to compare the effect of Fluticasone Furoate/ Vilanterol Inhalation Powder 100/25mcg with placebo on Survival in Subjects with moderate Chronic Obstructive Pulmonary Disease (COPD) and a history of or at increased risk for cardiovascular disease.

Volunteers between the ages of 40 to 80 with COPD (Chronic Obstructive Pulmonary Disease) are invited to participate in a UI study investigating the  effects of 2 medications you breath into your lungs daily (Fluticasone Furoate (FF)/Vilanterol (VI) inhalation powder 100/25mcg QD) compared with a placebo. The study will involve multiple visits over the next 4 years. Compensation is available for those individuals who qualify for the study.  For more information please call Kim Sprenger at 319-353-8862 or by e-mail at kimberly-sprenger@uiowa.edu.

age group:40 to 80 years trial start date:April 17, 2012
Gender Preference:none Trial End Date: October 1, 2013
Contact Info:

Kim Sprenger RN

Research Coordinator

319-353-8862

1-800-777-8442 ask for pager 7587

Keywords: COPD ; Heart Disease ; Lung Disease ; Pulmonary Disease

Evaluate the Safety and Tolerability of Oral BAY63-2521

Principal Investigator: Sif Hansdottir, MD

Chest -2 Long-term Extension, Multicentre, Multi-international Study to Evaluate the Safety and Tolerability of Oral BAY63-2521 (1mg, 1.5 mg, 2.0 mg, 2.5 mg Tid) in Patients With Chronic Thromboembolic Pulmonary Hypertension (CTEPH)

Patients who have completed 16 weeks of treatment in the double blind trial CHEST 1

Riociguat (BAY63-2521)

BAY63-2521 - 1 mg tid - 2,5 mg tid orally until end of study

for more information go to www.clinicaltrials.gov Identifier NCT00910429

age group:18 to 80 years trial start date:April 11, 2012
Gender Preference:none Trial End Date: September 1, 2014
Contact Info:

Pulmonary Hypertension Program

Cynthia Larew RN  319-356-1028 pager # 2123

cynthia-larew@uiowa.edu

 

Keywords: Chest -2 Long-term Extension ; Chronic Thromboembolic Pulmonary Hypertension ; CTEPH ; Heart ; High blood pressure in lungs ; PH ; pulmonary hypertension

Biology Study of Transient Myeloproliferative Disorder (TMD) in Children with Down Syndrome

Principal Investigator:Ayman El-Sheikh, MD

AAML08B1 - Biology Study of Transient Myeloproliferative Disorder (TMD) in Children with Down Syndrome (DS)

This study is organized by Children's Oncology Group (COG). COG is an international research group that conducts clinical trials for children with cancer. Participants in this study are children who have been diagnosed with a condition called Transient Myeloproliferative Disorder (TMD).

TMD is found in young babies (less than 3 months old) with Down syndrome and is caused by abnormal blood cells that travel throughout the body. TMD can be life threatening if a subject develops any of the following symptoms: swelling of the organs, enlarged liver, and/or heart and lung problems. The condition of TMD in children with Down syndrome is not well understood. More information about TMD would help doctors to determine the best study treatment for TMD in the future. The purpose of this study is to collect blood samples from TMD subjects for medical research.

age group:0 to 17 years trial start date:October 28, 2011
Gender Preference:none Trial End Date: October 28, 2021
Contact Info:

Julie de la Garza, 319-356-3749

Keywords: cancer ; Children ; down syndrome ; el-sheikh ; Transient Myeloproliferative Disorder (TMD)

Pulmonary Arterial Hypertension Quality Enhancement Research Initiative Extension Program (PAH QuERI Ext)

Principal Investigator: Sif Hansdottir, MD

This program intends to improve the management of pulmonary arterial hypertension (PAH) patients through an evidence-based approach aimed at achieving optimal World Health Organization (WHO) functional class (FC): 1. Improving FC III & IV patients to FC II, 2. Improving FC II patients to FC I, and 3. Maintaining FC II & FC I patients.

 

Please refer to www.clinicaltrials.gov identifier NCT01389206 for more information.

age group:18 to 99 years trial start date:June 1, 2011
Gender Preference:none Trial End Date: March 31, 2016
Contact Info:

Pulmonary Hypertension Program

Cynthia Larew, RN

phone:  319-356-1028

fax:  319-356-7087

email:  cynthia-larew@uiowa.edu

Keywords: Heart ; High blood pressure in lungs ; PAH ; PH ; Pulmonary arterial hypertension ; Pulmonary diseases ; Pulmonary hypertension
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