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Showing 1 - 5 of 225 results
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Tivozanib in Soft Tissue Sarcomas

Principal Investigator: Mohammed Milhem, MD


Participants in this research study have a type of cancer called soft tissue sarcoma that has spread (metastasized) or that is not eligible for removal by surgery. The purpose of this study is to determine how this type of soft tissue sarcoma responds to treatment with an investigational drug called tivozanib. In some lab and clinical studies, tivozanib has been shown to interfere with the growth of some types of tumors. Approximately 10 people will take part in this study conducted by investigators at the University of Iowa. Up to 54 research participants will take part in this study at 5 sites in the United States.

age group:18 to 99 years trial start date:April 7, 2014
Gender Preference:none Trial End Date: June 18, 2015
Contact Info:

Mohammed Milhem     319-356-2324     mohammed-milhem@uiowa.edu

Keywords: Cancer ; Enter keyword ; Milhem ; Phase 2 ; Phase ii ; Tivozanib

Gemcitabine, Ascorbate, Radiation Therapy for Pancreatic Cancer, Phase I

Principal Investigator:Joseph Cullen MD

Department:GI Surgery

Participants in this study have been diagnosed with adenocarcinoma of the pancreas, a type of pancreatic cancer. The purpose of this study is to see if using pharmacological ascorbate and gemcitabine chemoradiation is safe and effective in treating pancreatic cancer. Approximately 30 people will take part in this study at the University of Iowa.

age group:18 to 99 years trial start date:January 21, 2014
Gender Preference:none Trial End Date: October 31, 2017
Contact Info:

Joseph Cullen     319-353-8297

Keywords: Cancer ; Cullen ; Pancreatic ; phase 1 ; phase i

Fine Motor Skill Memory

Principal Investigator: Kelly Cole, PhD

Department:Health and Human Physiology

We are currently recruiting healthy participants for a research study that examines learning and memory of a fine motor skill. If you choose to participate, you will visit the laboratory for two consecutive days, for 30-60 minutes each day. During these sessions, you will complete a fine motor task repeatedly. If you are interested, please contact Sara at sara-hussain@uiowa.edu

age group:18 to 30 years trial start date:April 14, 2014
Gender Preference:none Trial End Date: October 14, 2014
Contact Info:

Sara at sara-hussain@uiowa.edu

Keywords: dexterity ; grasp ; memory ; motor learning


Principal Investigator:Jennifer Robinson, MD, MPH

Department:CPH/Dept. of Epidemiology

The Preventive Intervention Center at the University of Iowa is conducting a study to find out if a new test can predict who may develop cognitive problems due to Alzheimer's disease based on their genes. This research will also test an investigational medication to see if it can delay the symptoms of cognitive disorders.

Adults aged 65-83 may qualify to participate in this study.

Eligible participants receive at no cost:

Memory and thinking evaluations

Laboratory evaluations


Study medication

You may receive compensation for time and travel. The study will last about 5 years and include 5 clinic visits the first year, then 2 visits a year until the end of the study.

To learn more, email us at cph-cognitivehealth@uiowa.edu or call 319/353-8233 or 1-800/887-6917.

age group:65 to 83 years trial start date:January 10, 2014
Gender Preference:none Trial End Date: July 10, 2014
Contact Info:

Study Coordinator: Erin Balkenende 319-353-8233 (erin-balkenende@uiowa.edu)

Principal Investigator: 319-384-5030 (jennifer-g-robinson@uiowa.edu)

Keywords: aging ; Alzheimer ; cognitive health ; dementia ; memory ; older adults ; seniors

Central Sensitization and Individual Differences

Principal Investigator: Laura Frey Law

Department:Physical Therapy & Rehabilitation Science

Healthy volunteers ages 18 to 55, with no serious medical conditions or current pain, are invited to participate in a study involving temporary muscle soreness from an infusion of a slightly acidic or normal saline solution. Visits also include questionnaires, collecting a saliva sample, and sensations of pressure, heat or cold water on the arm. There will be three visits: approximately 1.5 hours/visit.

Compensation available. 

age group:18 to 55 years trial start date:April 2, 2014
Gender Preference:none Trial End Date: January 23, 2015
Contact Info:

Contact Jackie Loesche at 319-335-9795 or email jacquelyn-loesche@uiowa.edu

Keywords: central sensitization ; Enter keyword ; experimental muscle soreness ; pain perception ; personality traits
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