Major Areas of Research

  • T cell and cytokine regulation of B cell polyclonal activation
  • Stem cell transplantation for the treatment of autoimmune diseases
  • Mechanisms of tolerance induction and maintenance; role of cytokines
  • Clinical transplantation immunology, both solid organ and bone marrow transplantation; role of HLA and non-HLA polymorphisms
  • Molecular regulation of B lymphocyte activation and death
  • Abnormal regulation of gene transcription in autoimmunity
  • Molecular biology and immunology of persistent viral infections in rheumatic diseases
  • Immune cell stimulation by bacterial DNA
  • Rheumatologic educational curriculum development and testing