Pathology has historically been defined by the intersection of laboratory science and clinical medicine. Each new advancement in science that has had an impact on diagnostic medicine has spawned a new area of "laboratory medicine", from the application of light microscopy to immunohistochemistry, from serology to flow cytometry, and molecular genetics. In order for a pathology department to lead, and not just follow, it must create and maintain "germinal centers" of those sciences related to human biology and pathobiology. This difficult and fragile process is called "research". It is the strength of our Pathology Department that this process has happened in the past. We are fully committed to its continuation.