Neuro-Ophthalmology Research


H. Stanley Thompson, MD, professor emeritus and former director of Neuro-ophthalmology, established the Pupillography Laboratory in the late 1960s.

Dr. Randy H. Kardon directs the laboratory and conducts clinical and research evaluations of pupillary movements of the iris in health and disease. In addition, the computerized infrared instrumentation is now equipped to record dynamic eye movements, and eyelid movements in addition to the dynamics of pupil movements.


Dr. Michael Wall supervises the recording of evoked electrical responses from the visual cortex using multifocal visual evoked potentials, extracted to produce a visual field or perimetric test of a patients vision based on objective recording of the brain’s electrical responses to visual stimuli


Dr. Kardon uses a clinical form of pattern electroretinography (PERG) and of pattern visual evoked potentials (PVEP) recorded simultaneously for monitoring the electrical response from retinal ganglion cells (PERG) and the electrical response from the recipient visual cortex of the brain (PVEP). The measurement is used to evaluate for damage and recovery in different forms of optic neuropathy.


Our Ophthalmic Photographers perform structural analysis of the optic nerve, nerve fiber layer, and retina using optical coherence tomography in patients with either optic nerve disorders or retinal disease.

Many of our Neuro-ophthalmology and other faculty are investigators for the Center for the Prevention and Treatment of Visual Loss at the Iowa City Veterans Administration Medical Center.