Welcome to the website for the University of Iowa Comprehensive Stroke Center (CSC). The Stroke Center specializes in the treatment of patients who have suffered a stroke or who have a cerebrovascular disease. We focus on compassion, convenience, and comfort for the patient while delivering advanced treatments. Our Stroke Center is recognized as a leader in the treatment and prevention of stroke.
Stroke occurs when blood flow to the brain is interrupted, causing brain cells in the immediate area to die because they stop getting oxygen. Stroke can also occur when a vessel breaks and bleeds into the brain. One way to remember if you or someone you are with is having a stroke, is to 'Think FAST'. FAST refers to the 3 common symptoms of stroke and what to do (Face droop, Arm droop, Speech problems, (T)ime to call 911).
Please see the menu on the right side of the page to schedule an appointment or learn about our care team. Information about clinical trials is below.
What happens after a stroke
Below are the clinical trials the Stroke Center is currently conducting. Click on the associated link(s) to get more information and / or apply.
The Stroke Center at UIHC recently achieved Advanced Certification Comprehensive Stroke Center by The Joint Commission and the American Heart Association/American Stroke Association.
Comprehensive Stroke Center certification is given when centers meet the following criteria:
The Stroke Center is also part of the National Institutes of Health StrokeNet initiative. We are the regional coordinating center, more information can be found at the UIRCC site here: University of Iowa Regional Coordinating Center. StrokeNet is intended to streamline stroke research, by centralizing approval and review, lessening time and costs of clinical trials, and assembling a comprehensive data sharing system.
The Stroke Center offers referring physicians a 24/7 consultation with a stroke physician and our nurse coordinator facilitates transfer of patients to our care.
The center also utilizes telemedicine to provide remote consultation to stroke patients in other parts of the state or country. Please see for a demonstration of how this works.
The Stroke Center helps train fellows in our ACGME approved vascular fellowship program. For more information see the following link:
The UI Comprehensive Stroke Center (CSC) is a leader in both developing and conducting trials that test promising therapies for the prevention, treatment, and recovery of stroke. Researchers at the CSC have been at the forefront of translational and clinical research in cerebrovascular disease since the Cooperative Aneurysm study in the 1960s. The first dedicated stroke unit in the country was developed at our institution in the 1970s. In the 1980s our institution held Master Agreements in Stroke with NINDS. As part of this program, we have designed and directed Phase I, Phase II, and Phase III trials testing promising treatments for acute ischemic stroke and subarachnoid hemorrhage. An important accomplishment was the creation of the National Institutes of Health Stroke Scale (NIHSS), which was developed and tested by the NIH and investigators in Cincinnati and Iowa City. It is now the standard clinical assessment tool for determining the severity of neurological impairments with stroke and part of many clinical trials. Another accomplishment was the TOAST study (Trial of Org 10172 in Acute Stroke Treatment). TOAST was the first modern, Phase III trial of acute stroke treatment funded by an NINDS grant, which demonstrated the lack of effectiveness of anticoagulation in patients with acute ischemic stroke. The study also resulted in the creation of the TOAST classification of stroke subtype, which remains the primary system in use to categorize stroke mechanisms in trials, as well as in practice nationally and internationally.
Stroke quality measures at University of Iowa Hospitals and Clinics.
For more information, please see our About Your Neurology Visit guide.