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Síndrome de Waterhouse-Friderichsen

Definición

Es una insuficiencia de las glándulas suprarrenales debido a sangrado dentro de dichas glándulas.

Causas

Esta afección es causada por una grave infección con las bacterias meningococos u otra grave infección por bacterias, tales como:

• Estreptococos del grupo B
• Pseudomonas aeruginosa
• S. pneumoniae
• Staphylococcus aureus

En muy pocas ocasiones, el síndrome de Waterhouse-Friderichsen puede ser causado por el uso de medicamentos que favorecen la coagulación de la sangre. Otras causas abarcan:

• Conteos plaquetarios bajos
• Síndrome antifosfolípido primario
• Trombosis de la vena renal
• Uso de esteroides

Posibles complicaciones

Las complicaciones abarcan:

• Insuficiencia suprarrenal aguda
• Shock

Es mortal si no se trata de inmediato.

Figures

Referencias

Meurer WJ, Lavoie FW. Central nervous system infections. In: Marx JA, Hockberger Rs, Walls RM, et al, eds. Rosen's Emergency Medicine: Concepts and Clinical Practice. 7th ed. Philadelphia, Pa: Mosby Elsevier; 2009: chap 107.

Maitra A. The endocrine system. In: Kumar V, Abbas AK, Fausto N, Aster JC, eds. Robbins and Cotran Pathologic Basis of Disease. 8th ed. Philadelphia, Pa: Saunders Elsevier; 2009:chap 24.

White PC. Adrenocortical insufficiency. In: Kliegman RM, Behrman RE, Jenson HB, Stanton BF, eds. Nelson Textbook of Pediatrics. 19th ed. Philadelphia, Pa: Saunders Elsevier; 2011:chap 569.

Revision

Last reviewed 1/26/2012 by A.D.A.M. Editorial Team: David Zieve, MD, MHA, and David R. Eltz. Previously reviewed by Linda J. Vorvick, MD, Medical Director, MEDEX Northwest Division of Physician Assistant Studies, University of Washington School of Medicine; and Jatin M. Vyas, MD, PhD, Assistant Professor in Medicine, Harvard Medical School, Assistant in Medicine, Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital (8/24/2011).

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