Fibrinogen is a protein produced by the liver. This protein helps stop bleeding by helping blood clots to form. A blood test can be done to tell how much fibrinogen you have in the blood.
Serum fibrinogen; Plasma fibrinogen; Factor I; Hypofibrinogenemia test
How the Test is Performed
A sample of blood will be taken from your vein.
How to Prepare for the Test
There are no special steps you need to prepare for this test.
How the Test will Feel
You might feel slight pain or a sting when the needle is inserted to draw blood. You may feel throbbing afterward.
Why the Test is Performed
Your doctor may order this test if you have problems with blood clotting such as excessive bleeding.
The normal range is 200 - 400 milligrams per deciliter (mg/dL).
Note: Normal value ranges may vary slightly among different laboratories. Talk to your doctor about the meaning of your specific test results.
The examples above show the common measurements for results for these tests. Some laboratories use different measurements or may test different specimens.
What Abnormal Results Mean
Abnormal results may be due to:
- Excessive fibrinogen use (as in disseminated intravascular coagulation, DIC)
- Fibrinogen deficiency (from birth, or acquired after birth)
The test may also be performed for placenta abruption.
There is very little risk involved with having your blood taken. Veins and arteries vary in size so it may be harder to get a blood sample from one person than another.
Other risks slight risks from having blood drawn may include:
- Excessive bleeding
- Fainting or feeling light-headed
- Hematoma (blood accumulating under the skin)
- Infection (a slight risk any time the skin is broken)
Note: This test is most often performed on people who have bleeding disorders. The risk of excessive bleeding is slightly greater in such people than for those who do not have bleeding problems.
Gailani D, Neff AT. Rare coagulation factor deficiencies. In: Hoffman R, Benz EJ Jr, Silberstein LE, Heslop HE, Weitz JI, eds. Hematology: Basic Principles and Practice. 6th ed. Philadelphia, Pa: Saunders Elsevier; 2012:chap 139.
Ravi MV. Hemorrhagic disorders: Coagulation factor deficiencies In: Goldman L, Schafer AI, eds. Cecil Medicine. 24th ed. Philadelphia, Pa: Saunders Elsevier; 2011:chap 177.
Last reviewed 3/3/2013 by Yi-Bin Chen, MD, Leukemia/Bone Marrow Transplant Program, Massachusetts General Hospital. Also reviewed by A.D.A.M. Health Solutions, Ebix, Inc., Editorial Team: David Zieve, MD, MHA, Bethanne Black, Stephanie Slon, and Nissi Wang.
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