Hantavirus is a life-threatening disease spread to humans by rodents that has symptoms similar to influenza.
Hantavirus pulmonary syndrome; Hemorrhagic fever with renal syndrome
Causes, incidence, and risk factors
Hantavirus is carried by rodents, especially deer mice. The virus is found in their urine and feces, but it does not make the animal sick.
It is believed that humans can get sick with this virus if they come in contact with contaminated dust from mice nests or droppings. You may come in contact with such dust when cleaning homes, sheds, or other enclosed areas that have been empty for a long time.
Hantavirus does not spread between humans.
Rodents carrying the hantavirus have been found in many U.S. national parks. Campers and hikers may be more likely to catch the disease than most people. This is because they pitch tents on the forest floor and lay their sleeping bags down in musty cabins.
However, only a couple of cases have been directly linked to camping or hiking. Most people who are exposed to the virus have come in contact with rodent droppings in their own homes.
The early symptoms of hantavirus disease are similar to the flu and include:
- Muscle aches
People with hantavirus may begin to feel better for a very short amount of time, but within 1-2 days, it becomes hard to breathe. The disease gets worse quickly. Symptoms include:
- Dry cough
- General ill feeling (malaise)
- Nausea and vomiting
- Shortness of breath
Signs and tests
The health care provider will perform a physical exam. This may reveal:
- Acute respiratory distress syndrome (ARDS)
- Kidney failure
- Low blood pressure (hypotension)
- Low blood oxygen levels, which cause the skin to turn a blue color
The following tests may be done:
- Blood tests to check for signs of hantavirus
- Complete blood count (CBC)
- Complete metabolic panel
- Kidney and liver function tests
- X-ray of the chest
People with hantavirus are admitted to the hospital, often to the intensive care unit (ICU).
Treatments will include:
- Breathing tube or breathing machine in severe cases
- A medication called ribavirin to treat kidney-related problems and reduce the risk of death
There is no effective treatment for hantavirus infection involving the lungs.
Hantavirus is a serious infection that gets worse quickly. Lung failure can occur and may lead to death. Even with aggressive treatment, more than half of people who have this disease in their lungs die.
Complications of hantavirus may include:
- Kidney failure
- Heart and lung failure
These complications can lead to death.
Calling your health care provider
Call your health care provider if you develop flu-like symptoms after you come in contact with rodent droppings or rodent urine, or dust that is contaminated with these substances.
Avoid exposure to rodent urine and droppings.
- When hiking and camping, pitch tents in areas where there are no rodent droppings.
- Avoid rodent dens.
- Drink disinfected water.
- Sleep on a ground cover and pad.
- Keep your home clean. Clear out potential nesting sites and clean your kitchen.
If you must work in an area where contact with rodent urine or feces is possible, follow these recommendations from the Centers for Disease Control and Prevention (CDC):
Bell M. Viral hemorrhagic fevers. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier;2007:chap 404.
Peters CJ. California encephalitis, hantavirus pulmonary syndrome, and bunyavirid hemorrhagic fevers. In: Mandell GL, Bennett JE, Dolin R, eds. Douglas and Bennett's Principles and Practice of Infectious Disease. 7th ed. Philadelphia, Pa: Saunders Elsevier; 2009:chap 166.
Last reviewed 3/11/2011 by David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; Jatin M. Vyas, MD, PhD, Assistant Professor in Medicine, Harvard Medical School; Assistant in Medicine, Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
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