How Is Pulmonary Hypertension Treated?

Treatment of pulmonary hypertension depends on the cause. If the cause is left heart disease or lung disease, the focus is on treating the underlying disease. If the pulmonary hypertension is from chronic blood clots, the best treatment is blood thinners and possibly surgery. This type of surgery is only done in a few places in the world.

Medications used to treat pulmonary arterial hypertension come in several forms: oral (pill), inhaled, and infusions in a vein or under the skin. We will discuss all treatment options with you to determine which one is best for your condition and lifestyle.

  • Conventional therapies
  • Specialized medicines
    • Prostacyclins: stimulate cells that cause blood vessels to expand
    • Endothelin Receptor Antagonists (ERAs): block endothelin, which is a chemical that causes blood vessels to narrow
    • Phosphodiesterase 5 Inhibitors (PDE-5 inhibitors): relax the walls of blood vessels
    • Soluble guanylate cyclase (sGC) stimulators: stimulate chemicals in the lungs that relax the blood vessels
  • Surgical therapies

Pulmonary Hypertension Program home.

Health Library

Location and Contact

UI Heart and Vascular Center, Carver Pavilion
Elevator D, Level 4
If you have any questions please contact our nurse coordinator, Traci Stewart, RN

Care Team




  • Cynthia Larew, RN
  • Anne Lovig, RN
  • Page Scovel, RN
  • Traci Stewart, RN


  • Marti Bradbury, RD

Social Worker

  • Yuk Sum Chung, SW


  • Heather, Bream-Rouwenhorst, PharmD
  • Ryan Hobbs, Pharm

Other Team Members

  • Kim Schiltz
  • Kathi Jo Scott